Synthesis and Characterization of Ammonium Benzilate Bioactive Ionic Liquids and Their Antimicrobial Activity

The ammonium benzilate Ionic Liquids (ILs) was synthesized by the neutralization reaction of different cations of ethanolamine, dimethylethanolamine, and triethanolamine with benzillic acid. The reaction is monitored by thin layer Chromatography. The synthesized compounds were purified. Then the synthesized ILs was characterization by FT-IR Spectroscopy and 1H Nuclear Magnetic Resonance (NMR) Spectroscopy. Antibacterial screening of the test ILs was carried out with six human pathogenic bacteria, such as Bacillus cereus, Staphylococcus aureus, Escherichia coli, Salmonella typhi, Pseudomonas aeroginosa and Shigella dysenteriae and two phytopathogenic fungi like Aspergillus niger and Rhizopus azzahra. The minimum inhibitory concentration (MIC) was determined to establish a good bioactive molecule.