Okhonlaye, Ojokoh and Oluwatosin, Ojo (2018) Occurrence of Multidrug Resistant Staphylococcus aureus and Klebsiella pneumoniae Isolated from Clinical and Environmental Samples in Ondo State, Nigeria. Journal of Advances in Microbiology, 10 (2). pp. 1-10. ISSN 24567116
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Abstract
Introduction: Antibiotic resistant bacteria are threat to our community and hospital settings. Multi drug resistance in Klebsiella pneumoniae and Staphyloccous aureus can cause a wide range of infections, including pneumoniae, urinary tract infection and bacteremia which can lead to substantial morbidity and mortality.
Aims: To study multidrug resistance patterns of K. pneumoniae and S. aureus isolated from clinical (urine and post-operative wound) and environmental (air in hospital environment, market soil and well water) samples in Ondo State.
Place and Duration of Study: Sample: Department of Microbiology, Federal University of Technology, Akure, between November 2016 and July 2017.
Methodology: Collection of all the samples, isolation of K. pneumoniae and S. aureus and antibiotic susceptibility test were carried out using standard microbiological methods.
Results: S. aureus and K. pneumoniae counts were observed in Ondo North (wound; 50.20±0.00 ×104cfu) and Ondo central (well water; 42.33 ± 0.03×104cfu/ml) senatorial district respectively. K. pneumoniae recovery rate are; 23(23.71%) from market soil, 20(11.30%) from post-operative wound, 26(10.36%) from urine, 40(38.36%) from market well water and 13 (21.31%) hospital air while S. aureus was most prevalent in post-surgical wound 50 (28.25%). In Ondo north, K. pneumoniae isolates were at least 68% resistant to septrin, chloramphenicol, amoxacillin, and sparfloxacin while in south they were 70% resistant to septrin, chloramphenicol and amoxicillin however, all S. aureus isolates were 100% resistant to amoxicillin and were at least resistant to five different antibiotics. K. pneumoniae isolated from post-operative wound have resistance pattern of Septrin (71%), Chloramphenicol (13%), Amoxacillin (56%) and Sparfloxacin (56%) and in market soil the resistance pattern are; Augumentin (98%), Pefloxacin (99%), Septrin (98%), Chloramphenicol (97%), Gentamicin (100%), Ofloxacin (98%), Amoxacillin (98%), ciprofloxacin (98%), Sparfloxacin (98%) and Streptomycin (100%). All S. aureus isolated from urine samples were 100% resistant to streptomycin, chloramphenicol, ceftriazone, erythromycin, cotrimoxazole and Gentamicin.
Conclusion: Occurrence of these multidrug resistance K. pneumoniae and S. aureus in clinical and environmental samples could result into increase in morbidity and mortality.
Item Type: | Article |
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Subjects: | Science Global Plos > Biological Science |
Depositing User: | Unnamed user with email support@science.globalplos.com |
Date Deposited: | 12 May 2023 09:00 |
Last Modified: | 01 Feb 2024 04:22 |
URI: | http://ebooks.manu2sent.com/id/eprint/693 |