In vitro study on the anti-microbial efficacy of Aloe vera against Candida albicans

T., Jeevitha and K., Deepa and A., Michael (2018) In vitro study on the anti-microbial efficacy of Aloe vera against Candida albicans. African Journal of Microbiology Research, 12 (40). pp. 930-937. ISSN 1996-0808

[thumbnail of C09A62059163] Text
C09A62059163 - Published Version

Download (293kB)

Abstract

Oral Candida infections are common among the people who are immunocompromised, with poor oral hygiene, diabetics and advanced age. Even though several effective antifungal agents are available for treating oral Candida infections, on prolonged and frequent treatment with these drugs, they may result in development of drug resistant organisms. This leads to looking for an effective, inexpensive and simple alternative. Therapeutic products of plants play an important role in human health since ancient times. The present study was conducted to determine the bioactive components from the ethanol extract of Aloe vera by gas chromatograph-mass spectrometer (GC-MS) and to evaluate the antimicrobial effects of A. vera extracts on Candida albicans. GC-MS analysis revealed that ethanol extract of A. vera contains 26 bio active compounds. The results of in vitro antimicrobial activity of ethanol, methanol and aqueous extracts of A. vera against Candida albicans showed high inhibitory growth in yeast after treatment with ethanol extract followed by methanol extract with an inhibition zone of 23 and 12 mm, respectively. Aqueous extract did not show any zone of inhibition. The minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) of the extracts were also determined. From this study, it is concluded that, A. vera has potent antifungal activity against C. albicans.

Item Type: Article
Subjects: Science Global Plos > Biological Science
Depositing User: Unnamed user with email support@science.globalplos.com
Date Deposited: 29 Mar 2023 08:11
Last Modified: 28 Mar 2024 03:56
URI: http://ebooks.manu2sent.com/id/eprint/405

Actions (login required)

View Item
View Item