Mohammed, F. Z. and Gamal, Lamis and Mosa, Mohamed Farouk and Deen, I. M. El- (2020) Study of the Potential Role of Serum Neutrophil Gelatinase-Associated Lipocalin (NGAL) Levels in the Diagnosis and Prognosis of Breast Cancer in Egyptian Females "A Case-Control Study". Asian Journal of Research in Biochemistry, 7 (1). pp. 1-8. ISSN 2582-0516
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Abstract
Background: Breast cancer (BC) is the most common cause of malignancy in females all over the world. Continuous scientific research for the discovery of new markers helping is a cornerstone for early disease detection and proper management.
Aim of the Study: This study aimed to evaluate the role of Neutrophil gelatinase-associated lipocalin (NGAL) as prognostic markers for breast cancer in an Egyptian female population.
Patients and Methods: 120 BC patients and 30 healthy controls were the subjects of the study; serum NGAL levels were investigated and correlated with the clinicopathologic characteristics of the BC patients.
Results: Our study showed that NGAL was significantly different between healthy controls and BC patients, and it revealed a gradual increase with disease severity.
Conclusion: Our findings suggested that NGAL could be diagnostic marker for early case detection, and was shown to be associated with breast cancer prognosis, supporting its role as prognostic biomarker.
Item Type: | Article |
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Subjects: | Science Global Plos > Biological Science |
Depositing User: | Unnamed user with email support@science.globalplos.com |
Date Deposited: | 11 Mar 2023 10:24 |
Last Modified: | 23 Feb 2024 03:52 |
URI: | http://ebooks.manu2sent.com/id/eprint/306 |