Effect of Organotherapic Medicine on Glycaemia in Patients and Animals Receiving Antiretroviral Therapy

Aims: To evaluate the effect of an organotherapic drug, produced from the pancreas of a young pig,
on glycemic alterations in AIDS patients.
Methodology: Current study was carried out in a double-blind, placebo controlled and randomized
design. AIDS patients who had high fasting glucose (>110 mg/dL) were selected so that the effect of
the organotherapic drug could be evaluated. The patients were divided into two groups: Group I
comprised patients who received the organotherapic drug diluted in 1x1012 alcohol/ water 8%, once a
day, with a sublingual-administered fasting dose of 10 drops, during four months. Group II consisted
of patients receiving placebo once a day at the same dosage. Glucose oxidase method and ELISA,
following the manufacturer’s instructions, respectively determined levels of glucose and insulin before
treatment and monthly until four months after the start of treatment.
Results: Results registered hyperglycemia in 30% of the patients (60/200), higher than in the
population at large (7-15%). This fact could be related to the time of infection (10.0±4.78 years) and
treatment (9.3±3.76 years) of the patients. On the other hand, patients who underwent treatment with
organotherapic medicine showed a significant reduction (p<0,001) in blood glucose levels (from
204.5±86.63 to 86.63±16) and lower insulin levels after four months of treatment (organotherapic
group with 8.02±3.598 versus placebo with 23.83±3.670 p<0,001) within normality, regardless of age,
time of infection and time of treatment. This fact suggests that the organotherapic drug was effective
to stabilize blood glucose levels in patients.
Conclusion: Current study evidences that the organotherapic drug obtained from the pancreas of a
young pig, diluted 1x1012 in alcohol/ water 8% improves blood glucose levels in patients with
hyperglycemia keeping within the normal range after four months of treatment. Considering the
HAART therapy that significantly increases the life expectancy of AIDS patients but with significant
metabolic alterations this study shows the possibility of utilization of complementary and alternative
therapies. Although results indicate a significant effect of the organotherapic drug, additional studies
are needed to evaluate the long-term effects.