Acute Glomerulonephritis: A Study of Histo-Clinical Correlation of Patients at Tertiary Care Centre, India

Background: Acute glomerulonephritis is defined as the sudden onset of hematuria, proteinuria and red blood cell casts. This clinical picture is often accompanied by hypertension, edema and impaired renal function. Acute glomerulonephritis can be due to a primary renal disease or secondary to systemic diseases.

Aim: To study the clinical and histopathological correlation of acute glomerulonephritis in hospitalized patients.

Materials and Methods: This is a prospective study for a period of two years from Jan.2012 to Jan. 2014 performed in GMC Jammu.

Results: A total of 80 patients were included in this study. Out of 80 patients admitted as clinically suspected cases of acute glomerulonephritis (AGN). 9 patients responded to medical treatment.56 patients underwent renal biopsy. 10 patients diagnosed on renal biopsies as chronic glomerulonephritis and excluded on further analysis.46 patients diagnosed on renal biopsies as acute glomerulonephritis.

Conclusion: The patients with clinical presentations like edema, hematuria and hypertension have more evidence of acute glomerulonephritis on histopathological examination. PSAGN is the most common entity.