Gut Microbiota Profile - Autism Spectrum Disorder Relationship: Relative Lower Microbiota Diversity and Imbalance in Probiotics

Probiotic-based diet supplementation is among potential treatments of Autism Spectrum Disorders (ASDs) because of the existing gut microbiota profile-mental health relationships. In order to conceive personalized probiotic supplements to an autistic adult within a family of neurotypical father, mother and sister, a gut microbiota profiling and comparison has been carried out through fecal sample analyses. The latest 16S rRNA technology has been used for microbial determination at the species level (Mymicrozoo analysis, The Netherlands). Less microbiota diversity and an uncommon higher Streptococci/Lactobacilli abundance ratio have been revealed in the autistic adult compared to his relatives. These results have been discussed in relation to his digestive issues.