Udofia, Ofonimeh Emmanuel and Nwafor, Paul Alozie and Uffia, Ifiok Dominic and Elijah Nya, . (2023) Aphrodisiac Potentials of Methanol Extract of Homalium letestui Root in Male Rats. International Journal of Biochemistry Research & Review, 32 (5). pp. 68-78. ISSN 2231-086X
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Abstract
Aims: In this study, the methanol extract of Homalium letestui root was investigated with a view to ascertaining the scientific basis for its ethnobotanical use, and establishing, if any, the mechanisms of its effects, as an aphrodisiac.
Methodology: The crushed root of Homalium letestui was soaked in methanol for 72h and filtered with Whatman paper No.4; the extract was stored at -4oC. Mature male rats were divided into three groups (active, sluggish, and impotent) and administered with various doses of the extract. The rats were, thereafter, observed for the following: mount latency, intromission latency, ejaculation latency, post ejaculation latency, mount frequency, intromission frequency, erection frequency, and penile erection latency.
Results: The result showed that the Homalium letestui root extract (n-butanol, dichloromethane, ethyl acetate, petroleum ether and aqueous fractions) caused and maintained erection in the subjects, and their effects on the rats were dose-dependent and statistically significant (p<0.05-0.001). In addition, the aphrodisiac properties of the Homalium letestui root may in part be predicated on the properties of its phytochemical constituents which include alkaloids, saponins, flavonoids, tannins and cardiac glycosides.
Conclusion: These findings, therefore, justify the Homalium letestui root’s folkloric use as a sexual performance enhancer and demonstrate that the plant possesses aphrodisiac properties.
Item Type: | Article |
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Subjects: | Science Global Plos > Biological Science |
Depositing User: | Unnamed user with email support@science.globalplos.com |
Date Deposited: | 03 Oct 2023 07:55 |
Last Modified: | 03 Oct 2023 07:55 |
URI: | http://ebooks.manu2sent.com/id/eprint/1614 |