High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma

Marhuenda-Muñoz, María and Rinaldi de Alvarenga, José Fernando and Hernáez, Álvaro and Tresserra-Rimbau, Anna and Martínez-González, Miguel Ángel and Salas-Salvadó, Jordi and Corella, Dolores and Malcampo, Mireia and Martínez, José Alfredo and Alonso-Gómez, Ángel M. and Wärnberg, Julia and Vioque, Jesús and Romaguera, Dora and López-Miranda, José and Estruch, Ramón and Tinahones, Francisco J. and Lapetra, José and Serra-Majem, J. Lluís and Bueno-Cavanillas, Aurora and Tur, Josep A. and Sánchez, Vicente Martín and Pintó, Xavier and Delgado-Rodríguez, Miguel and Matía-Martín, Pilar and Vidal, Josep and Vázquez, Clotilde and Daimiel, Lidia and Ros, Emilio and Serra-Mir, Mercè and Vázquez-Ruiz, Zenaida and Nishi, Stephanie K. and Sorlí, Jose V. and Zomeño, María Dolores and Zulet, María Angeles and Vaquero-Luna, Jessica and Carabaño-Moral, Rosa and Notario-Barandiaran, Leyre and Morey, Marga and García-Ríos, Antonio and Gómez-Pérez, Ana M. and Santos-Lozano, José Manuel and Buil-Cosiales, Pilar and Basora, Josep and Portolés, Olga and Schröder, Helmut and Abete, Itziar and Salaverria-Lete, Itziar and Toledo, Estefanía and Babio, Nancy and Fitó, Montse and Martínez-Huélamo, Miriam and Lamuela-Raventós, Rosa M (2021) High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma. Antioxidants, 10 (3). p. 473. ISSN 2076-3921

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Abstract

Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have beneficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to increase their bioavailability via facilitating transfer to the aqueous micellar phase during digestion. However, the extent to which high fat intake may contribute to increased carotenoid plasma concentrations is still unclear. The objective was to examine the degree to which the consumption of different amounts of both carotenoid-rich foods and fats is associated with plasma carotenoid concentrations within a Mediterranean lifestyle context (subsample from the PREDIMED-Plus study baseline) where consumption of F&V and fat is high. The study population was categorized into four groups according to their self-reported consumption of F&V and fat. Carotenoids were extracted from plasma samples and analyzed by HPLC-UV-VIS-QqQ-MS/MS. Carotenoid systemic concentrations were greater in high consumers of F&V than in low consumers of these foods (+3.04 μmol/L (95% CI: 0.90, 5.17), p-value = 0.005), but circulating concentrations seemed to decrease when total fat intake was very high (−2.69 μmol/L (−5.54; 0.16), p-value = 0.064). High consumption of F&V is associated with greater systemic levels of total carotenoids, in particular when fat intake is low-to-moderate rather than very high.

Item Type: Article
Subjects: Science Global Plos > Agricultural and Food Science
Depositing User: Unnamed user with email support@science.globalplos.com
Date Deposited: 06 Jul 2023 04:51
Last Modified: 02 Nov 2023 06:19
URI: http://ebooks.manu2sent.com/id/eprint/1305

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