The Efficacy of Ultrasound Guided Platelet Rich Plasma Injection Versus Perineural Dextrose Injection in the Treatment of Severe Carpal Tunnel Syndrome

Shandal, Manar Elsayed and Hablas, Shaimaa Ahmed and Elbarbary, Amal Mohamed and Kassem, Elham Mohammed (2022) The Efficacy of Ultrasound Guided Platelet Rich Plasma Injection Versus Perineural Dextrose Injection in the Treatment of Severe Carpal Tunnel Syndrome. Journal of Advances in Medicine and Medical Research, 34 (21). pp. 74-87. ISSN 2456-8899

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Abstract

Aims: To compare the ultrasound-guided platelet rich plasma efficacy to ultrasound guided 5% dextrose perineural injection therapy in severe idiopathic carpal tunnel syndrome patients.
Patients and Methods: This research involved 60 patients with severe idiopathic CTS diagnosed by electrophysiological study. Patients were evaluated at three months after injection clinically, electrophysiological, and US examinations.

Patients were divided into 2 groups according to line of treatment:

Group I: 30 patients (34 hands) treated by two ultrasound guided injection with 3 mL PRP two weeks apart.

Group II: 30 patients (35 hands) treated by two ultrasound guided perineural injection therapy with 3 ml of 5% dextrose two weeks apart.

Results: There was significant clinical improvement (BCTQ and, VAS), electrophysiological improvement (DML, AMP, sensory amplitude and sensory conduction velocity of median nerve) and, ultrasonic improvement (CSA and FR) 3 month after treatment as compared to before treatment in both groups with better improvement in group 1.

There was significant difference between the 2 groups regarding VAS for pain and VAS for paresthesia 3 months after treatment with better improvement in PRP group. There was significant difference between the 2 groups regarding BCTQ 3 months after treatment with better improvement in PRP group.

Conclusion: Ultrasound guided injection of PRP or dextrose 5% is an effective and safe treatment for severe idiopathic CTS.

-Both modalities lead to significant reduction in pain, paresthesia, disability and also significant improvement in electrophysiological and ultrasound parameters of the median nerve with better improvement in PRP group.

Item Type: Article
Subjects: Science Global Plos > Medical Science
Depositing User: Unnamed user with email support@science.globalplos.com
Date Deposited: 14 Mar 2023 12:35
Last Modified: 27 Feb 2024 04:34
URI: http://ebooks.manu2sent.com/id/eprint/338

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